TARKINAID publications

  • Mustafa MB, Porter SR, Smoller BR, Sitaru C. Oral mucosal manifestations of autoimmune skin diseases. Autoimmun Rev. 2015 Oct;14(10):930-51. doi: 10.1016/j.autrev.2015.06.005. Epub 2015 Jun 24. Review. PubMed PMID: 26117595.

  • Dănescu S, Chiorean R, Macovei V, Sitaru C, Baican A. Role of physical factors in the pathogenesis of bullous pemphigoid: Case report series and a comprehensive review of the published work. J Dermatol. 2015 Jul 15. doi: 10.1111/1346-8138.13031. [Epub ahead of print] PubMed PMID: 26173987

    Mazzi P, Caveggion E, Lapinet-Vera JA, Lowell CA, Berton G. The Src-Family Kinases Hck and Fgr Regulate Early Lipopolysaccharide-Induced Myeloid Cell Recruitment into the Lung and Their Ability To Secrete Chemokines. J Immunol. 2015 Sep 1;195(5):2383-95. doi: 10.4049/jimmunol.1402011. Epub 2015 Jul 31.

  • Nussbaum CF, Bannenberg S, Keul P, Gräler MH, Gonçalves-de-Albuquerque CF, Korhonen H, von Wnuck Lipinski K, Heusch G, de Castro Faria Neto HC, Rohwedder I, Göthert JR, Prasad VP, Haufe G, Lange-Sperandio B, Offermanns S, Sperandio M, Levkau B. Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin. Nat Commun. 2015 Apr 2;6:6416. doi: 10.1038/ncomms7416.
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  • Pruenster M, Kurz AR, Chung KJ, Cao-Ehlker X, Bieber S, Nussbaum CF, Bierschenk S, Eggersmann TK, Rohwedder I, Heinig K, Immler R, Moser M, Koedel U, Gran S, McEver RP, Vestweber D, Verschoor A, Leanderson T, Chavakis T, Roth J, Vogl T, Sperandio M. Extracellular MRP8/14 is a regulator of β2 integrin-dependent neutrophil slow rolling and adhesion. Nat Commun. 2015 Apr 20;6:6915. doi: 10.1038/ncomms7915
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  • Lastrucci C, Baillif V, Behar A, Al Saati T, Dubourdeau M, Maridonneau-Parini I, Cougoule C. Molecular and cellular profiles of the resolution phase in a damage-associated molecular pattern (DAMP)-mediated peritonitis model and revelation of leukocyte persistence in peritoneal tissues. FASEB J. 2015 May;29(5):1914-29. doi: 10.1096/fj.14-259341. Epub 2015 Jan 21

  • Proag A, Bouissou A, Mangeat T, Voituriez R, Delobelle P, Thibault C, Vieu C, Maridonneau-Parini I, Poincloux R. Working together: spatial synchrony in the force and actin dynamics of podosome first neighbors. ACS Nano. 2015 Apr 28;9(4):3800-13. doi: 10.1021/nn506745r. Epub 2015 Mar 27.

  • Proag A, Bouissou A, Vieu C, Maridonneau-Parini I, Poincloux R. Evaluation of the force and spatial dynamics of macrophage podosomes by multi-particle tracking. Methods. 2015 Sep 2. pii: S1046-2023(15)30072-4. doi: 10.1016/j.ymeth.2015.09.002. [Epub ahead of print]

  • Vérollet C, Souriant S, Bonnaud E, Jolicoeur P, Raynaud-Messina B, Kinnaer C, Fourquaux I, Imle A, Benichou S, Fackler OT, Poincloux R, Maridonneau-Parini I. HIV-1 reprograms the migration of macrophages. Blood. 2015 Mar 5;125(10):1611-22. doi: 10.1182/blood-2014-08-596775. Epub 2014 Dec 19.

  • Vérollet C, Souriant S, Raynaud-Messina B, Maridonneau-Parini I. HIV-1 drives the migration of macrophages. Med Sci (Paris). 2015 Aug-Sep;31(8-9):730-3. doi: 10.1051/medsci/20153108010. Epub 2015 Sep 4. French.

  • Lastrucci C, Bénard A, Balboa L, Pingris K, Souriant S, Poincloux R, Al Saati T, Rasolofo V, González-Montaner P, Inwentarz S, Moraña EJ, Kondova I, Verreck FA, Sasiain Mdel C, Neyrolles O, Maridonneau-Parini I, Lugo-Villarino G, Cougoule C. Tuberculosis is associated with expansion of a motile, permissive and immunomodulatory CD16(+) monocyte population via the IL-10/STAT3 axis. Cell Res. 2015 Dec;25(12):1333-51. doi: 10.1038/cr.2015.123. Epub 2015 Oct 20

  • Vérollet C, Le Cabec V, Maridonneau-Parini I. HIV-1 Infection of T Lymphocytes and Macrophages Affects Their Migration via Nef. Front Immunol. 2015 Oct 6;6:514. doi: 10.3389/fimmu.2015.00514. eCollection 2015. Review
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  • Oliveira GP, Silva JD, Marques PS, Gonçalves-de-Albuquerque CF, Santos HL, Vascocellos AP, Takiya CM, Morales MM, Pelosi P, Mócsai A, de Castro-Faria-Neto HC, Rocco PR. The Effects of Dasatinib in Experimental Acute Respiratory Distress Syndrome Depend on Dose and Etiology. Cell Physiol Biochem. 2015;36(4):1644-58.

  • Garcia DG, de Castro-Faria-Neto HC, da Silva CI, de Souza e Souza KF, Gonçalves-de Albuquerque CF, Silva AR, de Amorim LM, Freire AS, Santelli RE, Diniz LP, Gomes FC, Faria MV, Burth P. Na/K-ATPase as a target for anticancer drugs: studies with perillyl alcohol. Mol Cancer. 2015 May 15;14:105. doi: 10.1186/s12943-015-0374-5.
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  • Gonçalves-de-Albuquerque CF, Silva AR, Burth P, Castro-Faria MV, Castro-Faria-Neto HC. Acute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammation. Mediators Inflamm. 2015;2015:260465. doi: 10.1155/2015/260465. Epub 2015 Nov 12. Review
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  • Gonçalves-de-Albuquerque CF, Cassiano F , Silva AR, Burth P, Rocco PRM, Castro-Faria MV, Castro-Faria-Neto HC. Possible mechanisms of Pseudomonas aeruginosa-associated lung disease. Int J Med Microbiol. 2016 Jan;306(1):20-8. doi: 10.1016/j.ijmm.2015.11.001. Epub 2015 Nov 22.

  • Hoffmann K, Hertl M, Sitaru C. Molecular diagnosis of autoimmune dermatoses. Hautarzt. 2016 Jan;67(1):33-9. doi: 10.1007/s00105-015-3723-9. German.

    Hoffmann K, Hertl M, Sitaru C. Molecular diagnosis of collagen vascular diseases and vasculitides. Hautarzt. 2016 Jan;67(1):40-52. doi: 10.1007/s00105-015-3728-4. German.

  • Mócsai A, Walzog B and Lowell CA Intracellular signalling during neutrophil recruitment. Cardiovasc Res 2015, 107: 373-385. doi: 10.1093/cvr/cvv159. Epub 2015 May 21. Review
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  • Varga A, Gyulavári P, Greff Z, Futosi K, Németh T, Simon-Szabó L, Kerekes K, Szántai-Kis C, Brauswetter D, Kokas M, Borbély G, Erdei A, Mócsai A, Kéri G, Vántus T: Targeting vascular endothelial growth factor receptor 2 and protein kinase D1 related pathways by a multiple kinase inhibitor in angiogenesis and inflammation related processes in vitro. PLoS One 2015, 10: e0124234. doi: 10.1371/journal.pone.0124234. eCollection 2015.
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  • Weber FC, Németh T, Csepregi JZ, Dudeck A, Roers A, Ozsvári B, Oswald E, Puskás LG, Jakob T, Mócsai A and Martin SF Neutrophils are required for both the sensitization and elicitation phase of contact hypersensitivity. J Exp Med 2015, 212: 15-22. doi: 10.1084/jem.20130062. Epub 2014 Dec 15.
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  • Da Silva A L, Magalhães RF, Branco VC, Silva JD, Cruz FF, Marques PS, Ferreira TPT, Morales MM, Martins MA, Olsen PC, Rocco PR. The tyrosine kinase inhibitor dasatinib reduces lung inflammation and remodelling in experimental allergic asthma. British Journal of Pharmacology, 2016, in press.

  • Holowacza S, Guigne C, Chene G, Mouysset S, Guilbot A, Seyrig C, Dubourdeau M. A multispecies Lactobacillus- and Bifidobacterium-containing probiotic mixture attenuates body weight gain and insulin resistance after a short-term challenge with a high-fat diet in C57/BL6J mice. PharmaNutrition 2016, in press.

  • Németh T, Futosi K, Sitaru C, Ruland J and Mócsai A Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo. Nat Commun 2016, in press.

  • Nanì S, Fumagalli L, Sinha U, Kamen L, Scapini P, Berton G Src Family Kinases and Syk Are Required for Neutrophil Extracellular Trap Formation in Response to β-Glucan Particles. J Innate Immun. 2015;7(1):59-73. doi: 10.1159/000365249. Epub 2014 Sep 24.

  • Vérollet C, Souriant S, Bonnaud E, Raynaud-Messina B, Kinnaer C, Fourquaux I, Ilme A, Benichou S, Jolicoeur P, Fackler O, Poincloux R, and Maridonneau-Parini I HIV-1 reprograms the migration of macrophages. Blood. 2015 Mar 5;125(10):1611-22. doi: 10.1182/blood-2014-08-596775. Epub 2014 Dec 19.

  • Weber FC, Németh T, Csepregi JZ, Dudeck A, Roers A, Ozsvári B, Oswald E, Puskás LG, Jakob T, Mócsai A and Martin SF Neutrophils are required for both the sensitization and elicitation phases of contact hypersensitivity. J Exp Med 2015, 212: 15-22.

  • Kovács M, Németh T, Jakus Z, Sitaru C, Simon E, Futosi K, Botz B, Helyes Z, Lowell CA and Mócsai A The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment. J Exp Med 2014, 211: 1993-2011.

  • Győri D, Csete D, Benkő S, Kulkarni S, Mandl P, Dobó-Nagy C, Vanhaesebroeck B, Stephens L, Hawkins PT and Mócsai A The phosphoinositide-3-kinase isoform PI3Kβ regulates osteoclast-mediated bone resorption in humans and mice.
    Arthritis Rheumatol 2014, 66: 2210-2221.
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  • Mócsai A, Kovács L and Gergely P What is the future of targeted therapy in rheumatology: biologics or small molecules? BMC Med 2014, 12: 43.
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  • Moraes L, Santos CL, Santos RS, Cruz FF, Saddy F, Morales MM, Capelozzi VL, Silva PL, de Abreu MG, Garcia CSNB, Pelosi P, Rocco PRM Effects of sigh during pressure control and pressure support ventilation in pulmonary and extrapulmonary mild acute lung injury. Crit Care 18(4):474, 2014 doi: 10.1186/s13054-014-0474-4.
    (PMID: 25113136)
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  • Santos CL, Moraes L, R.S. Santos RS, Samary CS, Silva JD, Morales MM, Capelozzi VL, de Abreu MG, Schanaider A, Silva PL, Garcia CS, Pelosi P, Rocco PRM The biological effects of higher and lower positive end-expiratory pressure in pulmonary and extrapulmonary acute lung injury with intra-abdominal hypertension. Crit Care.13;18(3):R121, 2014 doi: 10.1186/cc13920. (PMID: 24928415)
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  • Da Silva AL, Martini SV, Abreu SC, Samary C, Diaz BL, Fernezlian S, de Sá VK, Capelozzi VL, Boylan NJ, Goya RG, Suk JS, Rocco PRM, Hanes J, Morales MM DNA Nanoparticle-Mediated Thymulin Gene Therapy Prevents Airway Remodeling in Experimental Allergic Asthma. J Control Release. 180:125-33, 2014 doi: 10.1016/j.jconrel.2014.02.010. (PMID: 24556417)

  • Chiorean R, Mahler M, Sitaru C Molecular diagnosis of autoimmune skin diseases. Rom J Morphol Embryol, 55:1019-1033, 2014

  • Kovács M, Németh T, Jakus Z, Sitaru C, Simon E, Futosi K, Botz B, Helyes Z, Lowell CA, Mócsai A The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment. J Exp Med. 211(10):1993-2011, 2014 doi: 10.1084/jem.20132496.
    (PMID: 25225462)

  • Csorba K, Chiriac MT, Florea F, Ghinia MG, Licarete E, Rados A, Sas A, Vuta V, Sitaru C Blister-inducing antibodies target multiple epitopes on collagen VII in mice. J Cell Mol Med. 18(9):1727-1739, 2014. doi: 10.1111/jcmm.12338. (PMID: 25091020)
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  • Sitaru C, Thiel J The need for markers and predictors of Rituximab treatment resistance. Exp Dermatol. 23(4):236-237, 2014. doi: 10.1111/exd.12331.
    (PMID: 24450995)

  • Otten JV, Hashimoto T, Hertl M, Payne AS, Sitaru C Molecular diagnosis in autoimmune skin blistering conditions. Curr Mol Med. 14(1):69-95, 2014.
    (PMID: 24160488)
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  • Maridonneau-Parini I Control of macrophage 3D migration, a therapeutic challenge to limit tissue infiltration. Immunol. Rev. 262(1):216-231 2014 doi: 10.1111/imr.12214. (PMID: 25319337)

  • Troegeler A, Lastrucci C, Duval C, Tanne A, Cougoule C, Maridonneau-Parini I, Neyrolles O, Lugo-Villarino G An efficient siRNA-mediated gene silencing in primary human monocytes, dendritic cells and macrophages. Immunol. Cell Biol. 92(8):699-708, 2014 doi: 10.1038/icb.2014.39. (PMID:24890643)

  • Wiesner C, Le-Cabec V, El Azzouzi K, Maridonneau-Parini I, Linder S Macrophage migration and matrix degradation in 2D and 3D settings. Cell. Adh. Migr. 8(3): 179-191, 2014. (PMID: 24713854)

  • Park H, Dovas A, Hanna S, Lastrucci C, Cougoule C, Guiet R, Maridonneau-Parini I, Cox D Tyrosine phosphorylation of Wiskott-Aldrich syndrome protein (WASP) by Hck regulates macrophage function. J. Biol. Chem. 289(11):7897-7906, 2014 doi: 10.1074/jbc.M113.509497. (PMID: 24482227)

  • Maron-Gutierrez T, Silva J., Cruz, FF, Alegria S, Xisto DG, Assis EF, Castro-Faria-Neto HC, Dos Santos CC, Morales MM, Rocco PRM Insult-dependent effect of bone marrow cell therapy on inflammatory response in a murine model of extrapulmonary acute respiratory distress syndrome. Stem Cell Res Ther 4(5):123, 2013 doi: 10.1186/scrt334. (PMID: 24406030)
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  • Vérollet C, Gallois A, Dacquin R, Lastrucci C, Pandruvada SNM, Ortega N, Poincloux R, Behar A, Cougoule C, Lowell CA, Al Saati T, Jurdic P, Maridonneau-Parini I Hck contributes to bone homeostasis by controlling the recruitment of osteoclasts precursors. FASEB J. 27(9):3608-3618, 2013 doi: 10.1096/fj.13-232736.
    (PMID: 23742809)
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  • Fumagalli L, Campa CC, Germena G ,Lowell CA, Hirsch E, Berton G Class I Phosphoinositide-3-Kinases and Src Kinases Play a Nonredundant Role in Regulation of Adhesion-Independent and -Dependent Neutrophil Reactive Oxygen Species Generation. J. Immunol. 190(7):3648-3660, 2013 doi: 10.4049/jimmunol.1201951. (PMID: 23447687)
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  • Sesarman A, Sitaru C Induction of experimental epidermolysis bullosa acquisita by immunization with murine collagen VII. Methods Mol. Biol. 961:371-387, 2013. doi: 10.1007/978-1-62703-227-8_25. (PMID: 23325658)

  • Has C, Sitaru C Molecular dermatology comes of age. Methods Mol. Biol. 961:1-16, 2013. doi: 10.1007/978-1-62703-227-8_1. (PMID: 23325634)

  • Futosi K, Fodor S and Mócsai A Neutrophil cell surface receptors and their intracellular signal transduction pathways. Int. Immunopharmacol. 17(3):638-50, 2013 doi: 10.1016/j.intimp.2013.06.034. (PMID: 23994464)
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  • Futosi K, Németh T, Pick R, Vántus T, Walzog B and Mócsai A Dasatinib inhibits pro-inflammatory functions of mature human neutrophils.  Blood  119: 4981-4991, 2012. doi: 10.1182/blood-2011-07-369041. (PMID: 22411867)
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